New vaccine could quell Montezuma's Revenge
Travelers to Mexico sometimes fear the bandits of the highway. More likely they should fear the bandits of the bathrooms. Travelers' diarrhea is a bane to those traveling south of the border. If clinical trials of a new vaccine prove up as they have been, in the future you may be able to kiss Montezuma goodbye.Researchers at The University of Texas School of Public Health have found that patients given a travelers’ diarrhea vaccine were significantly less likely to suffer from clinically significant diarrhea than those who received placebo, according to a study published in this week’s edition of the Lancet. Happily, you don't need to get needled for the fix--it's a patch-based vaccine.
The study, which followed 170 healthy travelers ages 18-64 to Mexico and Guatemala, found that of the 59 individuals who received the novel vaccine, only three suffered from moderate or severe diarrhea, while roughly two dozen of the 111 who received a placebo suffered from moderate or severe diarrhea. Only one of the 59 volunteers in the vaccine group reported severe diarrhea, compared with 12 in the placebo group.
Of the few vaccinated patients who became sick, the diarrhea lasted only half a day on average, while those in the placebo group endured two days of illness and more than twice as many loose stools. Although not statistically significant, the frequency of new-onset irritable bowel syndrome, a long-term consequence of travelers’ diarrhea, was three times greater in placebo than vaccine recipients.The vaccine developer plans on phase 3 trials next year. If testing follows the typical pattern, hundreds if not thousands of folks will be involved to check for side effects as well as benefits. It could be a while before the "if and whens" of the approval process are completed. Meantime, hang onto the Pepto and remember, the expression is, "Donde es el baño?
Labels: Health
















